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Mr Jones is a 59-year-old man who was admitted 4 days ago following a motorcycle accident. He sustained a fractured R tibia and fibula. He underwent external fixation of the fracture 3 days ago. This morning he was complaining of some shortness of breath and chest pain. A 12 lead ECG showed non-specific ST segment and T wave changes, vital signs were Pulse: 110, B/P: 100/60, resp: 24, SaO2: 92. V/Q scan indicated pulmonary embolism. Past medical history: type 2 diabetes, peripheral vascular disease and impaired renal function GFR 60ml/min. He smokes 1 pack per day, but says he is going to give it up. Normally does little exercise and weighs 89kg.  


He has been commenced on Dalteparin 200 U/kg/day.


Discuss the rationale for commencing Dalteparin and outline the mechanism of action and nursing care required while on this drug 2022 latest answers