Neurotransmitters are the chemicals responsible for the transmission of all neuronal messages in the body. In an effort to always achieve homeostasis, the body can down-regulate or decrease the number of neurotransmitter receptor sites or maintain balance through re-uptake. What is re-uptake and how does this mechanism of action allow for selective serotonin re-uptake inhibitors (SSRIs) and serotonin-norepinephrine re-uptake inhibitors (SNRIs) to mitigate symptoms of unipolar depression? 

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