Miss Josepovic (80 year old) was admitted yesterday following a fall at home. She did not sustain any serious injury but has been kept in for monitoring, medication review and further investigations. Her past medical history is:, Congestive Heart Failure (CHF), mild renal impairment, hypertension, type 2 diabetes. Since admission she has been diagnosed with Atrial Fibrillation (AF)
Her medications are: Enalapril 10mg daily, Metformin 1g BD, Paracetamol 1g prn (max dose 4g in 24hors). She has commenced Dabigatran 150mg BD, Metoprolol 50mg BD.
Outline the mechanism of action of Dabigatran and Metoprolol and explain the rationale for commencing Miss Josepovic on these drugs. 2022 latest answers