Hypothesis: Senna and Fenugreek extracts will inhibit proliferation of the cancer cell and reduce the lipid peroxidatase levels as well as induce apoptosis in lung cancer cell line A549 and prostate cancer cell line PC3.

 

Aims of Study
Specific aim l.
Cell viability to determine if Senna and Fenugreek extracts reduce the viability of cancer cells in the three cancer cell lines, A549 (lung) and PC3 (prostate).
Specific aim 2.
ROS (Reactive Oxygen Species) Study the effect of Senna and Fenugreek extracts on the lipid peroxidase levels on the three cancer cell lines, A549 (lung) and PC3 (prostate).
Specific aim 3.
Apoptosis, look at the effect of Senna and Fenugreek extracts on the caspase-3 activation in the two cancer cell lines, A549 (lung and PC3 (prostate).